Raid Bosses
Sepulcher of the First Ones

Vigilant Guardian
Single Target / Cleave






Tank swap on Pneumatic Impact. You can use your different Sigils to help control the adds.

Skolex
Single Target






Never take 2 Riftmaws during the tank combo.
You can try to swap around to not stack up the bleed too much. However, it can be removed with things such as Blessing of Protection and Phial of Serenity.
Try to use Fiery Brand for every combo. Use Infernal Strike when you need to stack with the raid.

Artificer Xy'mox
Single Target / AoE / Cleave






Swap on Wormhole and Glyph.
Utilize all your Sigils during the intermission to help control the adds.

Dausegne
Single Target / Cleave






Swap on +5 stacks or so of Infused Strikes; when this debuff drops, it will explode for damage based on the number of stacks, so don't let it get too high.
The add spawns in front of the boss so keep that in mind when you're the one tanking.

Prototype Pantheon
Cleave






You fight against Prototype of War and Prototype of Duty during the first phase. You want to tank swap on every stack of Humbling Strikes from Duty. This ability damages the raid based on how much it did to the tank, so you want to use Fiery Brand and potentially other cooldowns for this. War is mostly just Gloom Bolts. You want to have people interrupt as it does a healing absorb.
During the second phase, you fight Prototype of Absolution and Prototype of Renewal. The tank swap here is Wracking Pain (like on Sire Denathrius if you ever did that boss), and you simply want to swap on every stack. Like in phase one, the other boss in this phase is mostly just a lot of interrupting required.
During the last phase, you fight all 4 of them together. The same mechanics happen, so make sure to do the tank swaps and have them stacked up so the raid can cleave them down with bloodlust.

Lihuvim
Single Target / AoE/ Cleave






This boss has 2 different tank swap mechanics. The first one is Deconstruction Energy, which is placed on the current tank as well as a random player. It can be used to destroy Unstable Motes when it explodes. Additionally, it will increase your physical damage taken by 100% for 10 seconds.
The second tank swap is Resonance. It will cast a combo of Kinetic Resonance > Sundering Resonance > Kinetic Resonance in that order.
Kinetic Resonance does a large amount of Physical damage and increases Cosmic damage taken. Sundering Resonance does a large amount of Cosmic damage and increases physical damage taken.
You want to do it this way: If tank 1 has debuff from Deconstruction Energy, tank 2 starts the combo and takes Kinetic Resonance, then tank 1 takes Sundering Resonance, and then tank 2 takes the second Kinetic Resonance.
Tldr; Deconstruction Energy debuff (tank1) > Kinetic Resonance (tank2) > Sundering Resonance (tank1) > Kinetic Resonance (tank2).
Make sure to pick up adds after intermission. You can use Sigil of Chains to help move and stack up the small Degeneration Automas.

Halondrus
Single Target






In phases 1 and 2, Halondrus casts Seismic Tremors, which are lines that go from the boss and outwards. These lines will create Ephemeral Fissures that spawn Ephemeral Motes. 2 of the lines will be white, and they will spawn 1 mote each per line with a shield that needs to be broken with the tank beam.
The tank swap is Lightshatter Beam, and you want to swap on every cast of it.
It is safe and recommended to taunt during the cast of the beam.
While all of this is happening, you also want to help block the motes from reaching the boss, as they will explode and do considerable raid damage.
You will still be “tanking” during the intermission as the boss will be using Lance to hit the tanks. It should generally be you as the monk doing this.

Anduin Wrynn
Single Target / Cleave / AoE






For most of the fight, when you're actively fighting Anduin, he has a stacking buff called Dark Zeal. This increases his attack speed, so you want to be swapping every now and then. In phase 1, he casts Blasphemy, which requires you to match with someone of the opposite debuff before the timer runs out.
Anduin casts Befouled Barrier on top of the active tank, which absorbs 75% of healing received inside of it, and will disappear once fully healed. You can step out of it if you start going low on hp. He will also cast Wicked Star, which shoots out from him and then travels back. You want to avoid these as they silence anything they hit.
At some point, he will cast Kingsmourne. Anyone who gets hit by it will be sent into a different phase where you have to deal with a couple of different adds. The smartest thing to do is have whichever tank is going in, to be the last one to tank the boss, so the stacks are reset outside for the other tank.
As the inside tank, you want to get aggro on the big add called Anduin's Despair and drag it around to the smaller adds that slowly move towards the middle. Once these adds have been dealt with, you will be sent back outside to resume phase 1. This will happen twice in this phase, and you need to alternate as you get a debuff that prevents you from going in again.
In the first Intermission, you will be fighting The Fallen King, and the tank swap mechanic here is Soul Reaper.
Note that this debuff lasts a couple of seconds longer compared to how often he casts it, so there will be some time when either of the 2 tanks will be tanking with a bit of this on them. There will also be a big add called Monstrous Soul that does more damage the less health it has. This add should be cleaved down and then focus nuked once it reaches 35% health. It should be tanked by the tank that doesn't currently tank The Fallen King.
Phase 2 is similar to phase 1, except you don't have to deal with Blasphemy; instead, you now have to deal with Grim Reflections, which casts a fear. You want to move around to them one at a time while interrupting and killing them, and the ones not being killed should be crowd-controlled. You don't want to keep the boss straight on top of these because if the Wicked Stars hit the Reflections, they will become immune to CC and interrupts.
You want to alternate going into the Kingsmourne phase like in phase 1 until you go into the 2nd Intermission.
The second Intermission is basically the same as the first one, except you now have to dodge March of the Damned. These are walking undead walls that will stun you and deal a ton of damage.
The last phase has the same tank swap mechanic as in the other phases on Anduin. It also has Blasphemy, except in this phase, everyone has the same debuff, and to get rid of it, they need to dispel themselves in the middle. The middle only has a set number of dispels, so it's worth noting that it is possible to survive when the debuff runs out, with either an immunity or a lot of stacked cooldowns.

Lords of Dread
Cleave






Both bosses have a tank swap, but it's only really the one from Mal'Ganis that matters.
Swap on every Leeching Claws from Mal'Ganis and make sure to not be in front of him when you have the buff, and the next frontal goes out as it will heal him.
Kin'Tessa has a frontal that applies a stacking debuff, and this one almost naturally falls off if you swap every Leeching Claws.
You want to bring the bosses to the end of the room on the pull, then slowly move around either clockwise or counterclockwise, so there's room for the rest of the raid to bait/drop debuffs.

Rygelon
Single Target






The tank swap on this boss is the Corrupted Strikes. It does some initial damage and then applies a low-duration dot with damage based on how much the initial hit was mitigated. If you fully absorb the hit, it won't apply a dot. Try to have Demon Spikes and Fiery Brand on as many of these as possible.
Keep the boss around the edges close to the Unstable Matter, so the raid is close enough to be able to kill it when needed.
When inside, make sure to soak the Gravitational Collapse when the Unstable Cores have been killed.
Use Fiery Brand and potentially be in Meta for this.

The Jailer
Single Target






The tank swap in phase 1 is Martyrdom.
Move the boss around so he's close to the holes in the ground for people to jump into with the debuff.
In phase 2, you want to swap on Shattering Blasts. The tank with the most mobility should be the one killing the Pylon furthest away to prevent them from reaching the middle.
The phase 3 tank swap is on Chains of Anguish; this one links you to other people based on proximity and makes them take any physical damage you take. Depending on raid cooldowns, you can break it by either going away from the raid, breaking all of the chains, or having the ones chained to you do them 1 at a time, depending on raid cooldowns. Move around the room as it will slowly be filled up with Defile. Use Sigil of Chains and Sigil of Silence to help out with the adds in this phase.
Sanctum of Domination

The Tarragrue
Single Target






I would more or less always go for DPS Anima Powers if possible, with the exceptions of Ever-Beating Heart and Unstable Form. Ever-Beating Heart is almost a must to have at least 1 of in the raid, and Unstable Form is just great to let you soak basically every Remnant during the encounter.
Notable tank DPS powers are Elethium Diffuser and Blade of the Lifetaker.
Swap during the cast of Overpower.
Use Fiery Brand before getting hit by Overpower

Eye of the Jailer
Single Target






Try to use Fiery Brand before Deathlink because the more damage you mitigate, the less the damage the raid takes. You also want to make sure to tank swap at 1 stack.
During the intermission, if your co-tank is a Brewmaster and you still have an Abductor alive, let him tank it as it's possible to dodge the debuff it applies.

The Nine
Single Target / Cleave






In the first phase you want to tank swap around 2-3 stacks of the debuff from Kyra, basically whenever the debuff drops. The same goes for Skyja when she joins the fight. At some point during the fight a big bubble will spawn that reduces the boss damage taken by 90%, you want to get her out of it as fast as possible. If your co-tank is a Brewmaster, have him speed taunt her out of the bobble.
Can assist with Sigil of Chains to grip the add closer to the boss if no Death Knights.

Remnant of Ner'zhul
Single Target






You basically want to tank swap after every Suffering.
When there's more than 1 orb up, try to move the boss on top of 1 of them and aim the Suffering towards the other to hit both of them. The off-tank should throw the orbs off the platform when destroyed.
Infernal Strike and Glide is your friend.

Soulrender Dormazain
Single Target






You want to tank swap after each cast of Ruinblade.
Drag the boss towards the middle before the adds spawn to have it as close to them as possible for fast and easy cleave. You can spec into Sigil of Chains to help you stack up adds if the group has no Death Knights.

Painsmith Raznal
Single Target






When the boss throws one of his weapons make sure you run to max range to reduce the fall off damage. You also want to tank swap after every weapon that is being cast.
In phase 1, the weapon hit causes a cross pattern of spikes across the platform.
In phase 2, the weapon hit causes a ripple effect of spikes that travels across the platform.
In phase 3, the weapon hit combines the 2 previous phases and does a cross pattern of spikes into the ripple effect.
You can Glide outside of the platform to get past the spikes.

Guardian of the First Ones
Single Target






The tank mechanic of this boss is a 4 part combo that goes: Sunder (Tank 1) > Obliterate Ttank1+half of the raid) > Obliterate (Tank 2+other half of the raid) > Sunder (tank2). You also want to make sure to taunt during the first Obliterate to not risk having it go on the same tank again.
Sunder is a big physical hit that puts a debuff on anyone who is hit by it, making them take 300% more damage for 20 seconds.
Obliterate also deals a large chunk of physical damage as well as split Arcane damage to anyone soaking it. It also adds a debuff making you take 5000% increased damage from Obliterate.
Use Fiery Brand for your part of the combo. Use it late so it covers both hits.

Fatescribe Roh-Kalo
Single Target






The tank swap mechanic on this fight is called Invoke Destiny. The boss will cast it on you and after 8 seconds an add will spawn and fixates on you. The raid will have to kill the add while you kite it around. When the spawned add dies it will spawn a bunch of small adds that needs to be killed as well.
I recommend running Sigil of Chains on this boss as it can allow you to grip in the small adds when the tank add dies.

Kel'Thuzad
Single Target






Soul Fracture is the tank swap mechanic of this fight and you want to make sure to taunt during the cast.
When the cast finishes, the tank who is targeted by the boss will receives 3 stacks of Soul Exhaustion. This debuff will increase damage taken by 500%. It also spawns 3 copies of the tank that needs to be interrupted and killed. When the adds are killed you need to pick up the souls to remove the debuff before the timer runs out.
You can spec into Sigil of Chains to help control the small adds. This fight is easy for Demon Hunters because they are so mobile. So, if your co-tank isn't very mobile consider doing the mechanics instead.

Sylvanas Windrunner
Single Target / AOE






Try to have Fiery Brand up for whenever you are getting hit by Ranger’s Heartseeker.
In phase 2 it's important that you get from one platform to the other as fast as you can so you can aggro the adds spawning before they kill the DPS.
Try to tank swap on Goliaths and Souljudge during this phase. If they die too slow they will get a stacking debuff/buff that makes them do more damage to their target.
Castle Nathria

Shriekwing
Single Target






Notes: You will want to have something for every Exsanguinating Bite, either Demon Spikes, Fiery Brand, Metamorphosis or Blood-Spattered Scale.

Huntsman Altimor
Cleave






Notes: You can use both Sigil of Misery as well as Imprison to crowd-control the Shades of Bargast. If you’re the only demon hunter in the raid, make sure to always apply Chaos Brand to all targets, Throw Glaive can be very useful for this!

Sun King's Salvation
Cleave






Notes: Most mobs can be gripped using Sigil of Chains during this boss fight. If you’re the only demon hunter in the raid, make sure to always apply Chaos Brand to all targets, Throw Glaive can be very useful for this!

Artificer Xy'mox
Single Target






Notes: Make use of the Dimensional Tear instead of using all your mobility to get away from the boss with the bomb. Instead, use your mobility to get back to the boss!

Hungering Destroyer
Single Target






Notes: You will want to have something for every Overwhelm, either Demon Spikes, Fiery Brand, Metamorphosis or Blood-Spattered Scale.

Lady Inerva Darkvein
Cleave






Notes: If you’re the only demon hunter in the raid, make sure to always apply Chaos Brand to all targets, Throw Glaive can be very useful for this!

The Council of Blood
Single Target






Notes: Make sure to bait the Evasive Lunge correctly to avoid extra raid-wide damage!

Sludgefist
Single Target






Notes: This is one of the hardest bosses to tank as a Demon Hunter as Sludgefist is non-stop high damage intake, if your co-tank is a Druid or a Monk, you should let them tank the boss primarily and you just taunt whenever they need it!

Stone Legion Generals
Single Target






Notes: Sigil of Chains can be used to grip the Stone Legion Skirmishers. Also always try to top yourself whenever a Stone Legion Goliath is about to hit 30% health as your incoming healing will be significantly decreased until that mob dies.

Sire Denathrius
Cleave






Notes: If you’re the only demon hunter in the raid, make sure to always apply Chaos Brand to all targets, Throw Glaive or Sigil of Flame can be very useful for this!