Blizzard has made a slightly more involved tier set in the 2nd raid of Dragonflight, it’s still basic but has some potential for talent swaps.
2 Piece Tier Set
It’s an automatic Symbols of Death use that gives you all the benefits of regular Symbols of Death (energy, crit chance from Planned Execution, Rotten, etc). It's something we play around slightly since it has some funny interactions with our actual Symbols of Death that it doesn't fully extend but only pandemics, so depending on which order you press them the pandemic range changes. If you go Shadow Dance -> Symbols of Death you can extend it by 3 seconds but if you go Symbols of Death -> Shadow Dance you can only extend it by 1.8 seconds
4 Piece Tier Set
So this is basically not something we care about, it’s just damage that happens.
In summary, the 10.1 tier set is underwhelming and doesn’t change much when it comes to gameplay. The 4-piece is also quite bad, so we end up running the new 2p + old 2p until you reach 441+ item level on the new tier set.
Beacon to the Beyond
Beacon to the Beyond drops from the last boss of the new raid and is a one-time huge damage hit on a 2.5-minute cooldown.
It’s a 2.5-second cast but can be used while on GCD so you at most lose 1.5 seconds when you could have done something else.
Elementium Pocket Anvil
Elementium Pocket Anvil is a damage proc and on-use trinket (doesn’t seem to share ICD with other trinkets) that has a chance to do Shadowflame damage when you use Gloomblade. Third best option behind Beacon to the Beyond.
Dragonfire Bomb Dispenser
Dragonfire Bomb Dispenser is an Instant on-use trinket that applies a debuff to your target, when it runs out, it explodes, doing a bunch of damage. Each time you critical strike, the cooldown is reduced, so you actually have to use this a lot during an encounter. The number 1 trinket, priority to get this one.
Neltharion’s call to suffering
Neltharion’s Call to Suffering is a main stat proc trinket that gives you a lot of main stat on a rather low uptime and it also deals damage to you while the proc is active. It’s a very strong trinket for AoE and Mythic+
Ominous Chromatic Essence
Ominous Chromatic Essence is just a stat stick trinket that gets more value the more people that have it in your group. It’s a very strong trinket for Mythic+
Slimy Expulsion boots for ST and AoE.
Toxified Armor Patch (can be placed on any armor piece, not weapons or rings) for ST and AoE.