Night Fae, Kyrian, and Venthyr are all excellent choices for Destruction for different kinds of fights.
All three of them are suitable for m+. However, currently, NF is the best universal choice for this type of content, being best in pure ST and cleave.
However, venthyr will be a better choice for pure AoE and dungeons like HoA or Gambit, where curses will also help your team deal with trash. Kyrian, on the other side, is currently a bit unknown; it’s a good choice if you can funnel it properly and will have the highest priority target damage; if you can execute it. However, you will lose on pure ST, cleave, and AoE to NF and Venthyr.
In the raid, your best choices will be NF and Kyrian. As I’ve said previously, NF will be best on ST and Cleave fights and Kyrian best on fights with ST+adds spawning and dying often enough for your funnel, like Dausegne or Rygelon.
Soulbinds and Conduits
Ashen Remains - always your best conduit regardless of situation.
Combusting Engine - good choice for ST without tier set.
Infernal Brand - very good conduit for any situation with tier set and good for AoE without tier set.
Demonic Momentum - your best finesse conduit.
Resolute Barrier - your first best defensive conduit.
Condensed Anime Sphere - your second best defensive conduit.
Bis NF soulbind tree:
Bis Venthyr soulbind tree for m+:
Bis Venthyr soulbind tree for raids:
Bis Kyrian soulbind tree:
- 2-Set - Ritual of Ruin - Casting Rain of Fire or Chaos Bolt gives you one stack per Soul Shard spent.
- 2-Set - Ritual of Ruin - After every 10 Soul Shards spent, the next casting of Rain of Fire or Chaos Bolt is instant, free, and will summon a Blasphemy.
Destro tier set is extremely good and is one of the best in the game. It increases your ST and 2 target damage and almost doubles your AoE damage.