Make sure to extend your Frenzy right before Ear Splitting Shriek.
You want to look out for Bloodgorge which makes this boss go immune. Don’t use any long cooldown right before as they will be wasted. This boss is really simple so there is nothing to add.
Huntsman AltimorSingle Target / Cleave
Sun King's SalvationAoE
Artificer Xy'moxSingle Target
On mythic difficulty as a hunter you are able to take Seed of Extinction 3 times.
First time use a Warlock Gateway then Disengage, for the second, use Aspect of the Cheetah and then Disengage and for the third time use Disengage and Aspect of the Turtle to avoid damage. That’s why Posthaste has a lot of value in this fight.
Hungering DestroyerSingle Target
Lady Inerva DarkveinSingle Target / Cleave
The Council of BloodSingle Target / Cleave
Whenever Sludgefist reaches 100 energy he will target a player and charge in their direction. This player will want to get behind a pillar so the boss smashes into it. When Sludgefist smashes into the pillar he gains Destructive Impact which makes him take 100% more damage for 12 seconds. You will want to line up your cooldowns for when he is vulnerable as it really makes a difference.